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Psoriasis is one of the most common dermatological conditions to affect children and can negatively impact development and QoL. Therefore, there is a need for evidence-based recommendations to guide the care of pediatric patients with psoriasis.1
The Spanish Academy of Dermatology and Venereology (AEDV) Psoriasis and Pediatric Working Groups developed a consensus document using a nominal group methodology combined with a systematic literature review. Experts were selected to provide insights based on their experience, with the aim of developing recommendations to act as guidance for dermatologists to support optimal therapy selection and standardize clinical practice for pediatric patients with psoriasis.1
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Key learnings |
Pediatric psoriasis significantly impacts on QoL and is associated with multiple comorbidities, including psoriatic arthritis, obesity, depression, and metabolic syndrome, necessitating individualized treatment with consideration of severity, patient age, comorbidities, preferences, and drug availability. |
Topical corticosteroids, calcipotriol, and biologic therapies (including etanercept, adalimumab, ustekinumab, secukinumab, ixekizumab) are recommended, with biologics increasingly preferred for moderate-to-severe cases, depending on patient characteristics and disease severity. |
Complete clearance (PASI100) is the optimal aim, but PASI90 or PASI75 may be acceptable in refractory cases. Long-term disease control is critical in children due to their ongoing physical and psychological development. Vaccination is also considered essential for infection control. |
Pediatric psoriasis is a multisystemic disease with unique clinical presentations and comorbidities, necessitating thorough assessment, including disease severity, QoL impact, and therapeutic response. Multidisciplinary care, including dermatologists, pediatricians, and psychologists, is essential to optimize outcomes. |
Abbreviations: PASI, Psoriasis Area and Severity Index; QoL, quality of life.
References
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