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ACR 2026 | Top abstracts: What’s hot in psoriatic disease?

By Amy Hopkins

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Nov 2, 2026


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To help navigate the exciting content being presented at the American College of Rheumatology (ACR) Convergence 2026, November 6–11, 2026, Orlando, US, the PsOPsA Hub Steering Committee have provided their recommendations for the top abstracts to look out for in psoriatic disease.

ACR 2026 | Top abstracts in psoriatic disease

Oral presentations: Sunday, November 8
Abstract TitlePresenterTime (EST)
0867Weight loss following GLP-1 receptor agonist initiation is associated with improved patient reported outcomes in rheumatoid arthritis and psoriatic arthritisJeffrey Curtis10:15–10:30
0879Identification of protein signatures tracking changes of disease activity of PsA disease domains and improvement with deucravacitinib treatment in phase 3 clinical studiesVinod Chandran08:45–09:00 
0881Difficult-to-treat psoriasis identifies patients at increased risk of incident psoriatic arthritis: A population-based time-varying cohort studyPaula David09:15–09:30
Oral presentations: Tuesday, November 10
Abstract TitlePresenterTime (EST)
2804Bimekizumab efficacy & safety versus risankizumab in patients with active psoriatic arthritis: 24-Week results from a head-to-head, multicenter, randomized, phase 3b studyJoseph Merola10:15–10:30
Oral presentations: Wednesday, November 11
Abstract TitlePresenterTime (EST)
2942Ixekizumab plus tirzepatide demonstrated greater disease control at 52 weeks versus ixekizumab alone with incremental improvement from Week 36 in adults with psoriatic arthritis and overweight or obesity: Results from a randomised clinical trialJoseph Merola09:45–10:00 
2943Biomarker-driven insights from the phase 2a AFFINITY study evaluating guselkumab + golimumab combination therapy versus guselkumab monotherapy in psoriatic arthritisIain McInnes10:00–10:15
Posters 
Abstract TitlePresenterDate and time (EST)
0344A phase 4, prospective, open-label study to assess the effectiveness of adding tirzepatide after initiation of ixekizumab in adults with psoriatic arthritis and overweight or obesityCatherine Bakewell

Sunday, November 8,

10:30–12:30

0348Baseline characteristics and 12-month effectiveness of guselkumab and IL-17 inhibitors among participants with oligoarticular psoriatic arthritis in the global PsABIOnd studyFrank Behrens

Sunday, November 8,

10:30–12:30

0358Effectiveness of guselkumab vs golimumab in participants with active psoriatic arthritis and inadequate response to one prior tumor necrosis factor inhibitor: Interim results at 6 months in a phase 3b, randomized, open-label, pragmatic trialAlexis Ogdie

Sunday, November 8,

10:30–12:30

0359Efficacy and safety of tildrakizumab in anti-TNF-naïve patients with active psoriatic arthritis: Week 52 results from a phase 3, randomized, double-blind, placebo-controlled trialPhilip Mease

Sunday, November 8,

10:30–12:30

0368Persistence, effectiveness, safety, and patient reported impact of guselkumab and IL-17 inhibitors in psoriatic arthritis: Full population results of the PsABIOnd global observational study over 12 monthsLaure Gossec

Sunday, November 8,

10:30–12:30

0373Treatment with glucagon-like peptide-1 receptor agonists is associated with lower disease activity and pain in psoriatic arthritis independent of weight changePankti Mehta

Sunday, November 8,

10:30–12:30

1306Bimekizumab demonstrated maintenance of clinical efficacy responses to 3 years in patients with active psoriatic arthritis from two phase 3 studiesJessica Walsh

Monday, November 9,

10:30–12:30

1310Cumulative days of musculoskeletal improvement in bio-naïve patients with PsA with or without metabolic syndrome and obesity receiving risankizumab through week 244: Integrated results from the KEEPsAKE clinical trialsSaakshi Khattri

Monday, November 9,

10:30–12:30

1312Efficacy and safety of guselkumab in participants with active psoriatic arthritis and inadequate response/intolerance to one prior tumor necrosis factor inhibitor through 1 year of the SOLSTICE studyBea Rivard

Monday, November 9,

10:30–12:30

1313Efficacy of izokibep, a novel IL-17A inhibitor, in patients with active psoriatic arthritis: Composite measures of disease activity and patient-reported outcomes from a randomized, double-blind, placebo-controlled, multicenter, phase 2b/3 studyPhilip Mease

Monday, November 9,

10:30–12:30

1314Envudeucitinib (ESK-001) in moderate-to-severe plaque psoriasis: 24-week results from the randomized, double-blind, active comparator- and placebo-controlled, phase 3 ONWARD1 and 2 studiesElisa Muscianisi

Monday, November 9,

10:30–12:30

1326Real-world effectiveness of risankizumab in patients with psoriatic arthritis: 6-month interim results from the observational PErsistence with RISankizumab (PERIS) studyCarlo Selmi

Monday, November 9,

10:30–12:30

2293Efficacy of apremilast in patients with early psoriatic arthritis: A post hoc pooled analysis of seven clinical trialsPhilip Mease

Tuesday, November 10,

10:30–12:30

2295Guselkumab efficacy on improvements in American College of Rheumatology response components and association with structural damage progression in participants with active and erosive psoriatic arthritis: Results from a phase 3b, randomized double-blind, placebo-controlled studyProton Rahman

Tuesday, November 10,

10:30–12:30

2297Ixekizumab and concomitant tirzepatide achieved early disease control in adults with psoriatic arthritis and obesity/overweight: phase 3b TOGETHER-PsA trialMohamed Sheesh

Tuesday, November 10,

10:30–12:30

2313Tildrakizumab for the treatment of prior anti-tumor necrosis factor-experienced or -naïve participants with active psoriatic arthritis: Pooled Week 24 results of two Phase 3, randomized, double-blind, placebo-controlled studies, INSPIRE 1 and INSPIRE 2Philip Mease

Tuesday, November 10,

10:30–12:30

LB12Icotrokinra, an IL-23 receptor targeted oral peptide, in biologic-naïve participants with active psoriatic arthritis: Results through Week 24 of a phase 3, randomized, double-blind, placebo-controlled studyJoseph F. Merola

Tuesday, November 10,

10:30–12:30

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This content is accurate as of the date of publication and is not updated retrospectively. Please refer to the latest available evidence, guidelines, and relevant regulatory information when making clinical decisions.